Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 9/20 | 0.76 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30896198 | 1.00 | MERTK (0.76) | MERTKNPY5RNPC1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8891541 | 0.99 | MERTK (0.74) | MERTKNPY5RNPC1ALDH1A1MAPT | |
| SCHEMBL27223332 | 0.89 | MERTK (0.63) | MERTKNPY5RALDH1A1MAPTMAPK1 | |
| SCHEMBL8889429 | 0.88 | MERTK (0.69) | MERTKNPY5RNPC1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8911047 | 0.87 | MERTK (0.68) | MERTKNPY5RNPC1ALDH1A1MAPT | |
| SCHEMBL8891059 | 0.85 | MERTK (0.66) | MERTKNPY5RNPC1ALDH1A1MAPT | |
| SCHEMBL8892661 | 0.85 | MERTK (0.56) | MERTKKMT2ABLMEGFRMEN1 | |
| Hydrochloric Acid SCHEMBL8909111 | 0.85 | MERTK (0.64) | MERTKNPY5RNPC1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8890483 | 0.84 | MERTK (0.56) | MERTKKMT2ABLMEGFRMEN1 | |
| SCHEMBL14256556 | 0.83 | MERTK (0.81) | MERTKNPY5RPDE5AACP1OGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | UNIV JEFFERSON (US) | 2024-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | ADRB2, ADRB1, ADRB3 | MERTK 3423/4885NPY5R 2011/4885NPC1 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.