Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 8/20 | 0.69 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.58 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | OGG1 | O15527 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.48 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
| ▸ | PGK1 | P00558 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890313 | 0.94 | MERTK (0.72) | MERTKNPY5RCXCR4PDE5AACP1 | |
| SCHEMBL8890736 | 0.86 | CAMK2D (0.51) | MERTKNPY5R | |
| SCHEMBL8889429 | 0.86 | MERTK (0.69) | MERTKNPY5RPDE5AACP1OGG1 | |
| Hydrochloric Acid SCHEMBL8911047 | 0.85 | MERTK (0.68) | MERTKNPY5RPDE5AACP1OGG1 | |
| SCHEMBL27224044 | 0.84 | MERTK (0.81) | MERTKNPY5RPDE5AACP1OGG1 | |
| SCHEMBL8889634 | 0.83 | MERTK (0.98) | MERTKNPY5RPDE5AACP1OGG1 | |
| SCHEMBL8890638 | 0.83 | NPY5R (0.67) | MERTKNPY5RTAAR1POLBHTT | |
| SCHEMBL8890443 | 0.82 | MERTK (0.64) | MERTKNPY5RPDE5AACP1OGG1 | |
| Hydrochloric Acid SCHEMBL8890334 | 0.82 | MERTK (0.95) | MERTKNPY5RPDE5AACP1OGG1 | |
| Hydrochloric Acid SCHEMBL8918566 | 0.82 | MERTK (0.63) | MERTKNPY5RPDE5AACP1OGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |