Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889472 | 1.00 | POLB (0.52) | POLBALDH1A1NPC1RAB9APKM | |
| SCHEMBL7117272 | 0.85 | POLB (0.57) | POLBALDH1A1NPC1RAB9APKM | |
| SCHEMBL1254966 | 0.85 | POLB (0.57) | POLBALDH1A1NPC1RAB9APKM | |
| SCHEMBL7876554 | 0.76 | POLB (0.57) | POLBALDH1A1NPC1RAB9APKM | |
| SCHEMBL7877016 | 0.75 | POLB (0.63) | POLBALDH1A1NPC1RAB9APKM | |
| SCHEMBL7876929 | 0.75 | POLB (0.63) | POLBALDH1A1NPC1RAB9APKM | |
| SCHEMBL2666190 | 0.74 | ALDH1A1 (0.71) | POLBALDH1A1NPC1RAB9APKM | |
| SCHEMBL26741146 | 0.74 | ALDH1A1 (0.60) | POLBALDH1A1NPC1RAB9APKM | |
| SCHEMBL26741187 | 0.74 | ALDH1A1 (0.60) | POLBALDH1A1NPC1RAB9APKM | |
| SCHEMBL7873377 | 0.73 | EPHX2 (0.48) | POLBALDH1A1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003966-A1 | N-(AMINO ACID) SUBSTITUTED SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |