SCHEMBL8889486

SCHEMBL8889486

Cc1cc(C(=O)C2=C(O)CCCC2=O)c(C)c2c1SCCC21SCCS1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1271214 0.84 SMN1; SMN2 (0.30)
SCHEMBL8346248 0.77 HPGD (0.33) MAPTHPGDTSHRTAAR1HSD17B10
SCHEMBL8351023 0.74 MAPT (0.36) MAPTHPGDTSHRTAAR1HSD17B10
SCHEMBL8399062 0.71 SMN1; SMN2 (0.31)
SCHEMBL8220757 0.67
SCHEMBL10053665 0.65
SCHEMBL8558295 0.65
SCHEMBL8457958 0.65 SMN1; SMN2 (0.30)
SCHEMBL8399488 0.62 MAPT (0.46) MAPTHPGDTSHRTAAR1HSD17B10
SCHEMBL1270526 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997001550-A1 HERBICIDAL KETALS AND SPIROCYCLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-01-16 WO disclosed