Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 3/20 | 0.31 |
| ▸ | RXRB | P28702 | 2/20 | 0.31 |
| ▸ | RXRG | P48443 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346248 | 0.78 | HPGD (0.33) | MAPTHPGDHSD17B10TSHRTAAR1 | |
| SCHEMBL8554515 | 0.77 | MAPT (0.41) | MAPTHPGDHSD17B10TSHRTAAR1 | |
| SCHEMBL8399431 | 0.75 | MAPT (0.31) | MAPTHPGDHSD17B10TSHRTAAR1 | |
| SCHEMBL8122960 | 0.68 | CXCR2 (0.30) | MAPTHPGDHSD17B10TSHRTAAR1 | |
| SCHEMBL8137796 | 0.66 | — | — | |
| SCHEMBL6726207 | 0.66 | RXRA (0.35) | KDM4EMEN1KMT2ATDP1RXRA | |
| SCHEMBL8344681 | 0.62 | RXRA (0.30) | MAPTRXRARXRBRXRG | |
| SCHEMBL6721464 | 0.62 | KDM4E (0.35) | HPGDHSD17B10ALDH1A1GAALMNA | |
| SCHEMBL16540927 | 0.60 | KDM4E (0.45) | MAPTHPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL625521 | 0.60 | KDM4E (0.48) | HPGDHSD17B10ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885936-A | BENZOTHIOPYRAN DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0860441-A1 | Herbicidal derivatives of 1,4-dithiino(2,3c)benzothiopyran | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-08-26 | — | — | EP | disclosed |