Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6726207 | 0.83 | RXRA (0.35) | KDM4EMEN1KMT2ATDP1NOTUM | |
| SCHEMBL8344681 | 0.78 | RXRA (0.30) | MAPT | |
| SCHEMBL8399488 | 0.78 | MAPT (0.46) | HPGDHSD17B10MAPTTSHRTAAR1 | |
| SCHEMBL8889486 | 0.77 | MAPT (0.31) | HPGDHSD17B10MAPTTSHRTAAR1 | |
| SCHEMBL8351023 | 0.76 | MAPT (0.36) | HPGDHSD17B10MAPTTSHRTAAR1 | |
| SCHEMBL8399431 | 0.75 | MAPT (0.31) | HPGDHSD17B10MAPTTSHRTAAR1 | |
| SCHEMBL6721464 | 0.74 | KDM4E (0.35) | HPGDHSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL9036741 | 0.72 | RARA (0.34) | MEN1KMT2ANOTUM | |
| SCHEMBL6721524 | 0.69 | RXRA (0.35) | HPGDMAPTTSHRKDM4EMEN1 | |
| SCHEMBL8122960 | 0.68 | CXCR2 (0.30) | HPGDHSD17B10MAPTTSHRTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952266-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-09-14 | — | — | US | disclosed |
| US-5885936-A | BENZOTHIOPYRAN DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0860441-A1 | Herbicidal derivatives of 1,4-dithiino(2,3c)benzothiopyran | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-08-26 | — | — | EP | disclosed |