Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18321308 | 0.83 | CYP1A2 (0.46) | ALDH1A3SMN1; SMN2KDM4E | |
| SCHEMBL97276 | 0.83 | CYP1A2 (0.46) | ALDH1A3SMN1; SMN2KDM4E | |
| SCHEMBL5803767 | 0.81 | ALDH1A1 (0.50) | ALDH1A3MAPK1CA12CA1CA2 | |
| SCHEMBL9844692 | 0.81 | ALDH1A3 (0.45) | ALDH1A3KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL14233591 | 0.81 | ALDH1A3 (0.45) | ALDH1A3KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL9421466 | 0.79 | ALDH1A3 (0.44) | ALDH1A3KMT2AMEN1CA12CA1 | |
| SCHEMBL94527 | 0.78 | ALDH1A3 (0.42) | ALDH1A3KMT2AMEN1KDM4EHPGD | |
| SCHEMBL3276265 | 0.78 | ALDH1A3 (0.42) | ALDH1A3KMT2AMEN1KDM4EHPGD | |
| SCHEMBL9365277 | 0.78 | ALDH1A3 (0.42) | ALDH1A3KMT2AMEN1KDM4EHPGD | |
| SCHEMBL10794800 | 0.76 | ACACB (0.42) | ALDH1A3KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691340-A | CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-25 | — | — | US | disclosed |