Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 4/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 3/20 | 0.33 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.33 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.33 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9080581 | 0.99 | ITGB3 (0.42) | ITGB3ITGA2BKCNH2ITGAVALPG | |
| SCHEMBL7335927 | 0.78 | PTGDR2 (0.39) | ITGB3ITGA2BKCNH2ITGAVHTT | |
| SCHEMBL7335413 | 0.77 | ITGB3 (0.52) | ITGB3ITGA2BKCNH2HRH3 | |
| SCHEMBL7334526 | 0.77 | ITGB3 (0.40) | ITGB3ITGA2BKCNH2ITGAVLMNA | |
| Hydrochloric Acid SCHEMBL7399509 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2BKCNH2HRH3 | |
| SCHEMBL8639763 | 0.73 | ITGB3 (0.43) | ITGB3ITGA2BKCNH2SMN1; SMN2HRH3 | |
| SCHEMBL8602874 | 0.72 | ITGB3 (0.44) | ITGB3ITGA2BKCNH2LMNAMAPT | |
| SCHEMBL7333641 | 0.71 | HRH3 (0.47) | ITGB3ITGA2BKCNH2LMNAMAPT | |
| SCHEMBL7400454 | 0.69 | HRH3 (0.48) | ITGB3ITGA2BKCNH2MAPTHRH3 | |
| SCHEMBL9078246 | 0.68 | ALDH1A1 (0.45) | ITGB3ITGA2BMAPTMAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652242-A | 3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL)PHENOXY)BURYIC ACID, AMIDE OR ESTER; INHIBITORS OF BINDING OF FIBRINOGEN TO GLYCOPROTEIN | ZENECA LIMITED (GB) | 1997-07-29 | — | — | US | disclosed |