Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279966 | 0.87 | RAB9A (0.56) | RAB9APOLBHPGDSMAPTNPC1 | |
| SCHEMBL8886596 | 0.84 | MAPT (0.64) | RAB9APOLBHPGDSMAPTNPC1 | |
| SCHEMBL4666632 | 0.81 | MAP4K4 (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8891567 | 0.80 | MAPT (0.60) | RAB9APOLBHPGDSMAPTNPC1 | |
| SCHEMBL20340353 | 0.79 | RAB9A (0.84) | RAB9APOLBHPGDSMAPTNPC1 | |
| SCHEMBL17280250 | 0.79 | RAB9A (0.53) | RAB9APOLBMAPTNPC1MAPK1 | |
| SCHEMBL17279967 | 0.78 | RAB9A (0.59) | RAB9APOLBHPGDSMAPTNPC1 | |
| SCHEMBL1608353 | 0.77 | MAPT (0.63) | RAB9APOLBMAPTNPC1MAPK1 | |
| SCHEMBL17279977 | 0.77 | MAPT (0.54) | RAB9APOLBMAPTNPC1MAPK1 | |
| SCHEMBL1181309 | 0.77 | RAB9A (0.77) | RAB9APOLBMAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |