Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | TTK | P33981 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26478317 | 0.85 | MAPT (0.51) | MAPTGAARAB9APOLBALDH1A1 | |
| SCHEMBL8886596 | 0.84 | MAPT (0.64) | MAPTGAARAB9APOLBHPGDS | |
| SCHEMBL8889679 | 0.80 | RAB9A (0.58) | MAPTRAB9APOLBHPGDSMEN1 | |
| SCHEMBL26467185 | 0.80 | MAPT (0.48) | MAPTGAARAB9APOLBALDH1A1 | |
| SCHEMBL20340353 | 0.79 | RAB9A (0.84) | MAPTRAB9APOLBHPGDSMEN1 | |
| SCHEMBL17279914 | 0.79 | MAPT (0.49) | MAPTGAARAB9ATTKMEN1 | |
| SCHEMBL17279967 | 0.78 | RAB9A (0.59) | MAPTRAB9APOLBHPGDSMEN1 | |
| SCHEMBL8889788 | 0.78 | RAB9A (0.64) | MAPTRAB9APOLBHPGDSL3MBTL1 | |
| SCHEMBL1608353 | 0.77 | MAPT (0.63) | MAPTGAARAB9APOLBMEN1 | |
| SCHEMBL10967551 | 0.77 | MAPT (0.60) | MAPTGAATTKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |