Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893348 | 0.90 | ALDH1A1 (0.43) | TSHRALDH1A1MAPTSCN1ASCN2A | |
| SCHEMBL8892991 | 0.89 | NPC1 (0.38) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8891781 | 0.88 | DHODH (0.36) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8890896 | 0.87 | TBXA2R (0.41) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8892594 | 0.87 | MAPT (0.35) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8889606 | 0.86 | TSHR (0.34) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8892962 | 0.86 | CA1 (0.39) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8889548 | 0.85 | DHODH (0.47) | CCR5MEN1KMT2ADHODHPOLB | |
| SCHEMBL8890935 | 0.84 | DHODH (0.36) | TSHRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8891081 | 0.84 | DHODH (0.41) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |