Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891781 | 0.89 | DHODH (0.36) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL8888828 | 0.89 | KDM4E (0.35) | NPC1KDM4ERAB9AALDH1A1TAS1R3 | |
| SCHEMBL8889700 | 0.89 | TSHR (0.42) | NPC1KDM4ERAB9AALDH1A1CYP1A2 | |
| SCHEMBL8891270 | 0.87 | TAS1R3 (0.33) | NPC1KDM4ERAB9AALDH1A1CYP1A2 | |
| SCHEMBL8891110 | 0.87 | DHODH (0.43) | NPC1KDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL8891167 | 0.86 | PTGDR2 (0.33) | NPC1KDM4ERAB9AALDH1A1CYP1A2 | |
| SCHEMBL8890712 | 0.86 | KDM4E (0.34) | NPC1KDM4ERAB9ATDP1TAS1R3 | |
| SCHEMBL8899642 | 0.86 | PDE2A (0.33) | NPC1KDM4ERAB9AALDH1A1CYP1A2 | |
| SCHEMBL8892076 | 0.86 | KDM4E (0.34) | NPC1KDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL8814987 | 0.86 | CSF1R (0.45) | NPC1RAB9AALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |