Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809088 | 0.88 | HSP90AA1 (0.33) | NPC1MAPTHTTRAB9ASMN1; SMN2 | |
| SCHEMBL8572771 | 0.80 | EDNRB (0.34) | HSP90AA1HSP90AB1NPSR1 | |
| SCHEMBL8812629 | 0.72 | HSP90AA1 (0.35) | SMN1; SMN2HSP90AA1HSP90AB1NPSR1FGFR1 | |
| SCHEMBL8321570 | 0.72 | NPC1 (0.35) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8810384 | 0.72 | NPSR1 (0.36) | MAPTLMNAHSP90AA1HSP90AB1NPSR1 | |
| SCHEMBL8810852 | 0.72 | NPSR1 (0.36) | SMN1; SMN2LMNAHSP90AA1HSP90AB1NPSR1 | |
| SCHEMBL8953395 | 0.71 | NPSR1 (0.33) | ALDH1A1NPSR1 | |
| SCHEMBL8324489 | 0.71 | KDM4E (0.34) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL996883 | 0.69 | POLM (0.34) | NPSR1 | |
| SCHEMBL8810119 | 0.68 | NPSR1 (0.35) | MAPTLMNAHSP90AA1HSP90AB1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627138-A | HERBICIDES | SANDOZ LTD. (CH) | 1997-05-06 | — | — | US | disclosed |
| US-5627137-A | HERBICIDES | SANDOZ LTD. (CH) | 1997-05-06 | — | — | US | disclosed |
| US-5561101-A | HERBICIDES | SANDOZ LTD. (CH) | 1996-10-01 | — | — | US | disclosed |
| US-5506192-A | HERBICIDES | SANDOZ LTD. | 1996-04-09 | — | — | US | disclosed |
| EP-0549524-A1 | Substituted phthalides and heterocyclic phthalides and their use in agriculture | SANDOZ LTD. (CH) | 1993-06-30 | — | — | EP | disclosed |