Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | GLA | P06280 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321570 | 0.86 | NPC1 (0.35) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8324080 | 0.82 | TUBB4A (0.35) | KDM4EMAPTPOLBMEN1KMT2A | |
| SCHEMBL8319636 | 0.82 | MAOB (0.36) | KDM4EMAPTMEN1KMT2AGLA | |
| SCHEMBL8889709 | 0.71 | NPC1 (0.33) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8809088 | 0.69 | HSP90AA1 (0.33) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8322076 | 0.68 | HCRTR1 (0.36) | KDM4EMAPTALDH1A1CES2 | |
| SCHEMBL8321836 | 0.65 | EDNRA (0.37) | MEN1KMT2AATMCES2 | |
| SCHEMBL8319030 | 0.65 | MAOB (0.38) | KDM4EMAPTMEN1KMT2AADORA2A | |
| SCHEMBL8918214 | 0.62 | CES2 (0.36) | CES2 | |
| SCHEMBL8801256 | 0.61 | HCRTR1 (0.35) | ADORA2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752424-B1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5877120-A | Nicotinic acid derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0752424-A1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-01-08 | — | — | EP | disclosed |