SCHEMBL996883

SCHEMBL996883

CCCCCC(=O)OC1(c2nc(OC)cc(OC)n2)OC(=O)c2c(Cl)ccc(Cl)c21

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.34
POLK Q9UBT6 2/20 0.34
POLL Q9UGP5 2/20 0.34
POLH Q9Y253 2/20 0.34
EPHX2 P34913 5/20 0.32
FPR1 P21462 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
HPGD P15428 1/20 0.31
MTNR1A P48039 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Acid SCHEMBL28115321 0.56 NR1H4 (0.50)
SCHEMBL8675342 0.56 POLM (0.54) POLMPOLKPOLLPOLHEPHX2
SCHEMBL10407331 0.55 KMT2A (0.60) POLMPOLKPOLLPOLH
SCHEMBL8676312 0.55 KDM4E (0.59) POLMPOLKPOLLPOLH
SCHEMBL15548447 0.55 POLM (0.53) POLMPOLKPOLLPOLHEPHX2
SCHEMBL6366589 0.55 POLM (0.71) POLMPOLKPOLLPOLH
SCHEMBL17138195 0.54 KMT2A (0.61) POLMPOLKPOLLPOLHEPHX2
SCHEMBL9716543 0.54 KMT2A (0.61) POLMPOLKPOLLPOLHEPHX2
SCHEMBL17138196 0.54 KMT2A (0.61) POLMPOLKPOLLPOLHEPHX2
SCHEMBL17138156 0.54 KMT2A (0.61) POLMPOLKPOLLPOLHEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5506192-A HERBICIDES SANDOZ LTD. 1996-04-09 US claimed
US-20140234225-A1 METHOD OF TREATMENT USING NANOPARTICULATE COMPOSITIONS HAVING LYSOZYME AS A SURFACE STABILIZER ALKERMES PHARMA IRELAND LIMITED (IE) 2014-08-21 US disclosed
US-8652464-B2 Method of treatment using nanoparticulate compositions having lysozyme as a surface stabilizer ALKERMES PHARMA IRELAND LIMITED (IE) 2014-02-18 US disclosed
US-20130224123-A1 NANOPARTICULATE COMPOSITIONS HAVING LYSOZYME AS A SURFACE STABILIZER ALKERMES PHARMA IRELAND LIMITED (IE) 2013-08-29 US disclosed
US-8323641-B2 Nanoparticulate compositions having lysozyme as a surface stabilizer ALKERMES PHARMA IRELAND LIMITED (IE) 2012-12-04 US disclosed
EP-2272342-B1 Herbicidal compositions BASF SE (DE) 2012-06-27 EP disclosed
EP-2050338-B1 Herbicidal compositions BASF SE (DE) 2011-05-25 EP disclosed
EP-2272342-A2 Herbicidal compositions BASF SE (DE) 2011-01-12 EP disclosed
EP-2272341-A2 Herbizide Zusammensetzungen BASF SE (DE) 2011-01-12 EP disclosed
US-7850995-B2 Bioadhesive nanoparticulate compositions having cationic surface stabilizers ELAN PHARMA INTERNATIONAL, LTD. (IE) 2010-12-14 US disclosed
US-5686387-A HERBICIDE POTENTIATORS BASF AKTIENGESELLSCHAFT (DE) 1997-11-11 US disclosed
US-5681793-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-10-28 US disclosed
US-5665673-A SEMICARBAZONES BASF AKTIENGESELLSCHAFT (DE) 1997-09-09 US disclosed
US-5665674-A SEMICARBAZONES SANDOZ LTD. (CH) 1997-09-09 US disclosed
US-5627138-A HERBICIDES SANDOZ LTD. (CH) 1997-05-06 US disclosed
US-5627137-A HERBICIDES SANDOZ LTD. (CH) 1997-05-06 US disclosed
US-5561101-A HERBICIDES SANDOZ LTD. (CH) 1996-10-01 US disclosed
US-5506192-A HERBICIDES SANDOZ LTD. 1996-04-09 US disclosed
EP-0646315-A1 Novel compositions containing an auxin transport inhibitor and another herbicide SANDOZ LTD. (CH) 1995-04-05 EP disclosed
EP-0614606-A2 Herbicidal compositions SANDOZ LTD. (CH) 1994-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140234225-A1 METHOD OF TREATMENT USING NANOPARTICULATE COMPOSITIONS HAVING LYSOZYME AS A SURFACE STABILIZER LPO, LCT, LIPA POLM 1481/4885POLK 1319/4885POLL 1299/4885
US-20130224123-A1 NANOPARTICULATE COMPOSITIONS HAVING LYSOZYME AS A SURFACE STABILIZER LPO, LCT, CTSA POLM 1431/4885POLK 1201/4885POLL 1179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.