SCHEMBL8889790

SCHEMBL8889790

O=C(Nc1ncc(Cl)cn1)c1cccc(F)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.71
RAB9A P51151 2/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
ALDH1A1 P00352 1/20 0.71
PKM P14618 1/20 0.71
TSHR P16473 1/20 0.71
KCNQ3 O43525 3/20 0.66
KCNQ2 O43526 3/20 0.66
KCNQ5 Q9NR82 2/20 0.66
KCNE1 P15382 2/20 0.63
KCNQ1 P51787 2/20 0.63
USP2 O75604 1/20 0.58
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
KDM4E B2RXH2 1/20 0.54
ALPL P05186 1/20 0.53
HDAC1 Q13547 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
KCNK3 O14649 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3164310 0.83 RAB9A (1.00) NPC1RAB9ASMN1; SMN2ALDH1A1PKM
SCHEMBL5346150 0.79 KCNQ3 (1.00) NPC1RAB9ASMN1; SMN2ALDH1A1PKM
SCHEMBL5215978 0.77 KCNQ3 (1.00) NPC1RAB9AALDH1A1KCNQ3KCNQ2
SCHEMBL30600561 0.77 SMN1; SMN2 (0.67) NPC1RAB9ASMN1; SMN2ALDH1A1PKM
SCHEMBL5649097 0.77 KCNQ3 (0.61) SMN1; SMN2ALDH1A1TSHRKCNQ3KCNQ2
SCHEMBL13155572 0.76 RAB9A (0.49) NPC1RAB9ASMN1; SMN2ALDH1A1PKM
SCHEMBL23405931 0.74 ADORA1 (0.60) KCNQ3KCNQ2KCNQ5KCNE1KCNQ1
SCHEMBL29743834 0.74 ADORA1 (0.60) KCNQ3KCNQ2KCNQ5KCNE1KCNQ1
SCHEMBL23405903 0.73 KCNQ3 (0.52) NPC1RAB9ASMN1; SMN2KCNQ3KCNQ2
SCHEMBL5651517 0.72 STAT3 (0.61) NPC1RAB9AALDH1A1KCNQ3KCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997003976-A1 SEMICARBAZONE DERIVATIVES AND PESTICIDES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1997-02-06 WO disclosed