Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891173 | 0.89 | CNR2 (0.65) | CNR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8889931 | 0.86 | ALDH1A1 (0.58) | KMT2ACYP3A4MEN1ALDH1A1SMPD1 | |
| SCHEMBL8891644 | 0.86 | MAPT (0.60) | CNR2KMT2AMAPTCYP3A4CYP2C9 | |
| SCHEMBL2814873 | 0.81 | SMN1; SMN2 (0.67) | KMT2AMAPTCYP3A4CYP2C9MEN1 | |
| SCHEMBL8892506 | 0.81 | PDE4B (0.76) | CNR2KMT2APDE4APDE4BPDE4C | |
| SCHEMBL7397574 | 0.80 | MAPT (0.64) | KMT2AMAPTCYP3A4CYP2C9MEN1 | |
| SCHEMBL13461264 | 0.80 | SMPD1 (0.67) | CNR2KMT2AMAPTPDE4APDE4B | |
| SCHEMBL1011139 | 0.80 | MAPT (0.60) | KMT2AMAPTPDE4APDE4BPDE4C | |
| SCHEMBL3372285 | 0.80 | MAPT (0.60) | KMT2AMAPTCYP3A4CYP2C9SMPD1 | |
| SCHEMBL56262 | 0.80 | MAPT (0.60) | CNR2KMT2AMAPTPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |