Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 9/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994630 | 0.88 | FKBP1A (0.50) | FKBP1AHPGDCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL26945273 | 0.87 | FKBP1A (0.49) | FKBP1APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8863318 | 0.87 | FKBP1A (0.49) | FKBP1APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6787776 | 0.81 | FKBP1A (0.49) | FKBP1AHPGD | |
| SCHEMBL204506 | 0.81 | FKBP1A (0.49) | FKBP1AHPGD | |
| SCHEMBL204505 | 0.81 | FKBP1A (0.49) | FKBP1AHPGD | |
| SCHEMBL8863781 | 0.81 | MMP2 (0.56) | KMT2A | |
| SCHEMBL2757477 | 0.80 | FKBP1A (0.47) | FKBP1ATDP1HPGDCYP3A4CYP2C9 | |
| SCHEMBL10137577 | 0.80 | FKBP1A (0.47) | FKBP1AHPGDCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8863381 | 0.80 | NPSR1 (0.48) | FKBP1AHPGDPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752419-A2 | Process for the preparation of N-substituted 4-ketoproline derivatives | Degussa Aktiengesellschaft (DE) | 1997-01-08 | — | — | EP | disclosed |