Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 6/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | ITK | Q08881 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | TEC | P42680 | 1/20 | 0.42 |
| ▸ | TXK | P42681 | 1/20 | 0.42 |
| ▸ | BMX | P51813 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | CD69 | Q07108 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8890553 | 0.99 | NPY5R (0.44) | NPY5RSYKBTKEGFRITK | |
| SCHEMBL8891253 | 0.92 | SYK (0.51) | NPY5RSYKBTKEGFRITK | |
| SCHEMBL8892661 | 0.82 | MERTK (0.56) | SYKEGFR | |
| Hydrochloric Acid SCHEMBL8890483 | 0.81 | MERTK (0.56) | SYKEGFR | |
| SCHEMBL8899460 | 0.79 | NPY5R (0.70) | NPY5R | |
| Hydrochloric Acid SCHEMBL6039334 | 0.78 | NPY5R (0.69) | NPY5R | |
| Hydrochloric Acid SCHEMBL6039207 | 0.78 | NPY5R (0.69) | NPY5R | |
| SCHEMBL8893944 | 0.78 | KMT2A (0.46) | NPY5R | |
| SCHEMBL8891133 | 0.77 | NPY5R (0.46) | NPY5RTNFSTK17AKDR | |
| Hydrochloric Acid SCHEMBL8905468 | 0.77 | KMT2A (0.45) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |