Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.86 |
| ▸ | LMNA | P02545 | 4/20 | 0.86 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503405 | 0.93 | KDM4E (1.00) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL8106730 | 0.86 | KDM4E (0.86) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL9831380 | 0.86 | KDM4E (0.86) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL9671672 | 0.83 | KDM4E (0.60) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL7221870 | 0.82 | KDM4E (0.54) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL9031442 | 0.81 | KDM4E (0.56) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL9672168 | 0.81 | ALDH1A1 (0.65) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL11007783 | 0.81 | KDM4E (0.77) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL10001050 | 0.80 | KDM4E (0.70) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL9033075 | 0.80 | KDM4E (0.55) | KDM4ELMNAGAAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325187-B1 | 4-ALKYL-1, 4-DIHYDROPYRIDINES WITH PAF-ANTAGONIST ACTIVITY | ALTER, S.A. (ES) | 1992-11-11 | — | — | EP | claimed |
| WO-1997007801-A1 | NEW APPLICATIONS OF 5-ETHOXYCARBONYL-2,4,6-TRIMETHYL-1,4-DIHYDROPYRIDINE-3-CARBOXYLATE OF 2-[N-(1,2-BENZISOTHIAZOLYL-3(2H)ONE-1,1-DIOXIDE]ETHYL | LABORATORIOS ALTER, S.A. (ES) | 1997-03-06 | — | — | WO | disclosed |
| EP-0253092-A1 | 1,4-Dihydropyridines, processes for their preparation and their use as antithrombotic drugs | ALTER, S.A. (ES) | 1988-01-20 | — | — | EP | disclosed |