Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.86 |
| ▸ | LMNA | P02545 | 5/20 | 0.86 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106730 | 1.00 | KDM4E (0.86) | KDM4ELMNAADORA3GAAPOLB | |
| SCHEMBL3503405 | 0.93 | KDM4E (1.00) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL9831160 | 0.89 | KDM4E (0.64) | KDM4ELMNAADORA3GAAPOLB | |
| SCHEMBL8890327 | 0.86 | KDM4E (0.86) | KDM4ELMNAADORA3GAAPOLB | |
| SCHEMBL3775215 | 0.85 | KDM4E (0.62) | KDM4ELMNAADORA3POLBALDH1A1 | |
| SCHEMBL9031442 | 0.81 | KDM4E (0.56) | KDM4ELMNAADORA3GAAPOLB | |
| SCHEMBL1663817 | 0.81 | LMNA (0.87) | KDM4ELMNAADORA3GAAPOLB | |
| SCHEMBL11007783 | 0.81 | KDM4E (0.77) | KDM4ELMNAADORA3GAAPOLB | |
| SCHEMBL432202 | 0.81 | KDM4E (0.66) | KDM4ELMNAADORA3GAAPOLB | |
| SCHEMBL9033301 | 0.80 | KDM4E (0.55) | KDM4ELMNAADORA3GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253092-B1 | 1,4-DIHYDROPYRIDINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTITHROMBOTIC DRUGS | ALTER, S.A. (ES) | 1991-09-25 | — | — | EP | disclosed |
| US-4782069-A | INHIBITION OF PLATELET ACTIVATION | ALTER, S.A. (ES) | 1988-11-01 | — | — | US | disclosed |
| EP-0253092-A1 | 1,4-Dihydropyridines, processes for their preparation and their use as antithrombotic drugs | ALTER, S.A. (ES) | 1988-01-20 | — | — | EP | disclosed |