Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | CRHBP | P24387 | 1/20 | 0.67 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170744 | 0.86 | KMT2A (1.00) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL4332105 | 0.85 | KMT2A (0.71) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL11609033 | 0.85 | KMT2A (0.64) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL1965205 | 0.83 | KMT2A (0.76) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL22382354 | 0.82 | MAPT (0.81) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL31424609 | 0.82 | KMT2A (0.67) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL15618391 | 0.81 | HCAR3 (0.73) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL9043092 | 0.81 | KMT2A (0.72) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL753425 | 0.81 | KMT2A (0.72) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL6170341 | 0.81 | KMT2A (0.59) | KMT2AALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602277-A | Substituted benzene derivatives useful as neuraminidase inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996030329-A1 | SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INCORPORATED (US) | 1996-10-03 | — | — | WO | disclosed |