Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891547 | 0.83 | KDM1A (0.42) | MAPTTP53NPY5RALKPDE5A | |
| Hydrochloric Acid SCHEMBL8920462 | 0.82 | KDM1A (0.42) | MAPTTP53NPY5RALKALDH1A1 | |
| SCHEMBL8898287 | 0.66 | HTR2A (0.41) | KDRMAPTTP53NPY5RALK | |
| SCHEMBL8890323 | 0.66 | NPY5R (0.45) | KDRNPY5REGFR | |
| SCHEMBL8898291 | 0.66 | CCR4 (0.38) | NPY5R | |
| Hydrochloric Acid SCHEMBL8890553 | 0.65 | NPY5R (0.44) | NPY5REGFR | |
| Hydrochloric Acid SCHEMBL8892373 | 0.64 | EGFR (0.49) | KDREGFRKDM4EALDH1A1KDM1A | |
| SCHEMBL8893944 | 0.62 | KMT2A (0.46) | NPY5RKDM4EALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8905468 | 0.62 | KMT2A (0.45) | NPY5RKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8893955 | 0.61 | NPY5R (0.40) | KDRNPY5RALKEGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |