Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889996 | 0.90 | SLC6A2 (0.32) | NR1H4NAMPTPDE2A | |
| SCHEMBL8892076 | 0.89 | KDM4E (0.34) | P2RX7NPC1LMNARAB9APOLB | |
| SCHEMBL8890374 | 0.88 | CCR5 (0.36) | HSP90AA1NAMPTPDE2A | |
| SCHEMBL8891972 | 0.87 | HCRTR2 (0.35) | NAMPT | |
| SCHEMBL8898866 | 0.87 | SLC6A2 (0.35) | — | |
| SCHEMBL8893425 | 0.86 | KDM4E (0.33) | HSP90AA1NPC1LMNARAB9ANAMPT | |
| SCHEMBL8894099 | 0.85 | PTGS2 (0.40) | P2RX7NR1H4NPC1LMNAPOLB | |
| SCHEMBL8890001 | 0.85 | KDM4E (0.36) | NPC1LMNARAB9ASMN1; SMN2PDE3B | |
| SCHEMBL8488431 | 0.85 | DHODH (0.34) | NAMPTPDE2A | |
| SCHEMBL8489456 | 0.85 | DHODH (0.34) | LMNASMN1; SMN2NAMPTPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |