Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878670 | 1.00 | MAPT (0.49) | MAPTGAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11883393 | 0.90 | NOX1 (0.51) | MAPTGAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2511248 | 0.79 | ALDH1A1 (0.55) | MAPTGAAKMT2AMEN1NOX1 | |
| SCHEMBL31351355 | 0.79 | SNCA (0.63) | MAPTGAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29242101 | 0.79 | SNCA (0.63) | MAPTGAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8889856 | 0.79 | CSNK1G1 (0.66) | MAPTGAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL25138231 | 0.78 | NOX1 (0.56) | MAPTGAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8230577 | 0.76 | CHEK1 (0.66) | MAPTKMT2ASMN1; SMN2MEN1NOX1 | |
| SCHEMBL11878147 | 0.76 | CHEK1 (0.66) | MAPTKMT2ASMN1; SMN2MEN1NOX1 | |
| SCHEMBL12683716 | 0.75 | ALDH1A1 (0.59) | MAPTGAAKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000252-A1 | TRICYCLIC INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1997-01-03 | — | — | WO | disclosed |