Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.81 |
| ▸ | GAA | P10253 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | MERTK | Q12866 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.62 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | GBA1 | P04062 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8889510 | 0.98 | NPY5R (0.79) | NPY5RGAAMAPTRECQLTAAR1 | |
| SCHEMBL2591063 | 0.90 | NPY5R (1.00) | NPY5RTAAR1MERTKMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6039677 | 0.89 | NPY5R (0.96) | NPY5RMAPTTAAR1MEN1KMT2A | |
| SCHEMBL8892916 | 0.88 | NPY5R (0.85) | NPY5RGAAMAPTRECQLTAAR1 | |
| Hydrochloric Acid SCHEMBL8898666 | 0.87 | NPY5R (0.83) | NPY5RGAAMAPTRECQLTAAR1 | |
| SCHEMBL8901062 | 0.86 | NPY5R (0.84) | NPY5RTAAR1MEN1KMT2AABCG2 | |
| SCHEMBL8898077 | 0.86 | NPY5R (0.84) | NPY5RMAPTMERTKMEN1KMT2A | |
| SCHEMBL8891079 | 0.85 | NPY5R (0.72) | NPY5RMAPTTAAR1MERTKMEN1 | |
| Hydrochloric Acid SCHEMBL8900449 | 0.84 | NPY5R (0.81) | NPY5RMAPTTAAR1MERTKMEN1 | |
| Hydrochloric Acid SCHEMBL8898758 | 0.84 | NPY5R (0.81) | NPY5RMAPTTAAR1MERTKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |