Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.84 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | PDE5A | O76074 | 2/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | KDM1A | O60341 | 1/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8900034 | 0.98 | NPY5R (0.81) | NPY5RABCG2MEN1KMT2APDE5A | |
| SCHEMBL2591063 | 0.92 | NPY5R (1.00) | NPY5RABCG2MEN1KMT2APDE5A | |
| Hydrochloric Acid SCHEMBL6039677 | 0.90 | NPY5R (0.96) | NPY5RABCG2MEN1KMT2APDE5A | |
| SCHEMBL8898077 | 0.87 | NPY5R (0.84) | NPY5RABCG2MEN1KMT2APDE5A | |
| SCHEMBL8897789 | 0.86 | NPY5R (0.66) | NPY5RABCG2MEN1KMT2APDE5A | |
| Hydrochloric Acid SCHEMBL8900449 | 0.86 | NPY5R (0.81) | NPY5RMEN1KMT2APDE5ASLC2A1 | |
| Hydrochloric Acid SCHEMBL8898758 | 0.86 | NPY5R (0.81) | NPY5RABCG2KMT2APDE5ASLC2A1 | |
| SCHEMBL8890734 | 0.86 | NPY5R (0.81) | NPY5RABCG2MEN1KMT2ASLC2A1 | |
| SCHEMBL8890555 | 0.86 | NPY5R (1.00) | NPY5RABCG2MEN1KMT2APDE5A | |
| SCHEMBL8890945 | 0.86 | NPY5R (1.00) | NPY5RABCG2MEN1KMT2ASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |