Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890772 | 1.00 | HSPA5 (0.49) | HSPA5MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL12724861 | 0.83 | HSPA5 (0.53) | HSPA5KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL1509747 | 0.79 | HSPA5 (0.50) | HSPA5MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL27558441 | 0.79 | HSPA5 (0.50) | HSPA5MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL11142669 | 0.76 | HSPA5 (0.48) | HSPA5KMT2ARAB9ANPC1FPR2 | |
| SCHEMBL2428932 | 0.76 | NPC1 (0.45) | HSPA5KMT2ARAB9AALDH1A1HTT | |
| SCHEMBL11252147 | 0.75 | PRMT5 (0.47) | HSPA5MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL6663162 | 0.73 | NPC1 (0.42) | HSPA5KMT2ASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL1822218 | 0.73 | — | — | |
| SCHEMBL1857157 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997005126-A1 | MUPIROCINSULFAMATES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1997-02-13 | — | — | WO | disclosed |