SCHEMBL8890965

SCHEMBL8890965

NC(=O)C1CCC(CNc2nc(NC(CO)CO)c3ccccc3n2)CC1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
VCP P55072 19/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8890983 0.87 TLR7 (0.45)
SCHEMBL8901739 0.85 TAAR1 (0.52) VCP
SCHEMBL8889919 0.85 VCP (0.52) VCP
SCHEMBL8891157 0.84 NPY5R (0.54) VCP
SCHEMBL8898260 0.83 VCP (0.50) VCP
SCHEMBL8891478 0.82 VCP (0.49) VCP
Hydrochloric Acid SCHEMBL8898939 0.82 VCP (0.48) VCP
SCHEMBL2636279 0.82 NPY5R (0.61) VCP
Hydrochloric Acid SCHEMBL2675355 0.81 NPY5R (0.60) VCP
SCHEMBL8898351 0.80 VCP (0.48) VCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997020823-A2 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS NOVARTIS AG (CH) 1997-06-12 WO claimed
WO-1997020823-A2 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS NOVARTIS AG (CH) 1997-06-12 WO disclosed