Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.74 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8900310 | 0.99 | NPY5R (0.72) | NPY5RKDM1AAURKAAURKB | |
| SCHEMBL8891826 | 0.89 | NPY5R (0.71) | NPY5RKDM1AAURKAAURKB | |
| Hydrochloric Acid SCHEMBL8889262 | 0.88 | NPY5R (0.70) | NPY5RKDM1A | |
| SCHEMBL8899654 | 0.88 | NPY5R (0.56) | NPY5RKDM1AAURKAAURKB | |
| SCHEMBL8891585 | 0.88 | NPY5R (0.77) | NPY5RKDM1A | |
| Hydrochloric Acid SCHEMBL8890045 | 0.87 | NPY5R (0.55) | NPY5RKDM1AAURKAAURKB | |
| Hydrochloric Acid SCHEMBL8890940 | 0.87 | NPY5R (0.75) | NPY5RKDM1A | |
| SCHEMBL8899982 | 0.86 | NPY5R (0.71) | NPY5RKDM1A | |
| Hydrochloric Acid SCHEMBL8890808 | 0.85 | NPY5R (0.70) | NPY5RKDM1A | |
| SCHEMBL8900176 | 0.85 | NPY5R (0.53) | NPY5RKDM1AAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |