Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.77 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.41 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8890940 | 0.99 | NPY5R (0.75) | NPY5RSLC2A1EGFRITKKDM1A | |
| SCHEMBL8889462 | 0.90 | NPY5R (0.62) | NPY5RKDM1ACTNNB1TCF7L2NEK2 | |
| Hydrochloric Acid SCHEMBL8890878 | 0.89 | NPY5R (0.61) | NPY5RSLC2A1KDM1ACTNNB1TCF7L2 | |
| SCHEMBL8890967 | 0.88 | NPY5R (0.74) | NPY5RKDM1A | |
| SCHEMBL8890077 | 0.87 | NPY5R (0.58) | NPY5REGFRITKCTNNB1TCF7L2 | |
| SCHEMBL8898853 | 0.87 | NPY5R (1.00) | NPY5RSLC2A1PDE5A | |
| Hydrochloric Acid SCHEMBL8900310 | 0.87 | NPY5R (0.72) | NPY5RKDM1A | |
| SCHEMBL8891429 | 0.87 | NPY5R (0.72) | NPY5REGFRITKKDM1ANEK2 | |
| SCHEMBL8899707 | 0.86 | NPY5R (0.58) | NPY5RSLC2A1CTNNB1TCF7L2 | |
| Hydrochloric Acid SCHEMBL8899629 | 0.86 | NPY5R (0.71) | NPY5RSLC2A1EGFRITKKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |