Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.71 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 2/20 | 0.41 |
| ▸ | MERTK | Q12866 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8890808 | 0.99 | NPY5R (0.70) | NPY5RSLC2A1GRK6MERTKKDM1A | |
| SCHEMBL8890967 | 0.86 | NPY5R (0.74) | NPY5RKDM1A | |
| Hydrochloric Acid SCHEMBL8900310 | 0.85 | NPY5R (0.72) | NPY5RKDM1A | |
| SCHEMBL8898853 | 0.83 | NPY5R (1.00) | NPY5RSLC2A1MERTKPDE5A | |
| Hydrochloric Acid SCHEMBL8900633 | 0.82 | NPY5R (0.98) | NPY5RSLC2A1MERTKHTTTAAR1 | |
| SCHEMBL8891909 | 0.78 | NPY5R (0.83) | NPY5RKDM4EPDE5A | |
| SCHEMBL8900516 | 0.76 | NPY5R (0.77) | NPY5R | |
| SCHEMBL8891585 | 0.76 | NPY5R (0.77) | NPY5RSLC2A1KDM1ANEK2PDE5A | |
| Hydrochloric Acid SCHEMBL8890109 | 0.75 | NPY5R (0.76) | NPY5R | |
| Hydrochloric Acid SCHEMBL8889724 | 0.75 | NPY5R (0.76) | NPY5RKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |