Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.54 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8890646 | 0.99 | NPY5R (0.53) | NPY5RSOS1SLC2A1MAPTSMN1; SMN2 | |
| SCHEMBL8891572 | 0.91 | NPY5R (0.60) | NPY5RSLC2A1EGFRCHEK2ERBB2 | |
| SCHEMBL8900235 | 0.90 | NPY5R (0.61) | NPY5RSLC2A1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8890113 | 0.87 | NPY5R (0.58) | NPY5RSOS1SLC2A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8906400 | 0.86 | NPY5R (0.57) | NPY5RSOS1SLC2A1MAPTSMN1; SMN2 | |
| SCHEMBL8891978 | 0.82 | NPY5R (0.65) | NPY5RSLC2A1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8900305 | 0.81 | EGFR (0.69) | NPY5RSLC2A1KMT2AEGFRCHEK2 | |
| Hydrochloric Acid SCHEMBL8899588 | 0.80 | CHEK2 (0.67) | NPY5RSLC2A1SMN1; SMN2KMT2AEGFR | |
| Hydrochloric Acid SCHEMBL8893122 | 0.79 | NPY5R (0.67) | NPY5RSLC2A1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8891059 | 0.79 | MERTK (0.66) | NPY5RSLC2A1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |