Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.60 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.55 |
| ▸ | ROS1 | P08922 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | MERTK | Q12866 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891002 | 0.91 | NPY5R (0.54) | NPY5RCHEK2EGFRERBB2ROS1 | |
| Hydrochloric Acid SCHEMBL8890646 | 0.91 | NPY5R (0.53) | NPY5RCHEK2EGFRERBB2ROS1 | |
| SCHEMBL8900235 | 0.91 | NPY5R (0.61) | NPY5REGFRERBB2AURKBCLK4 | |
| SCHEMBL8900305 | 0.88 | EGFR (0.69) | NPY5RCHEK2EGFRERBB2ROS1 | |
| SCHEMBL8891978 | 0.88 | NPY5R (0.65) | NPY5RSLC2A1PIN1MERTK | |
| Hydrochloric Acid SCHEMBL8899588 | 0.87 | CHEK2 (0.67) | NPY5RCHEK2EGFRERBB2ROS1 | |
| SCHEMBL8891059 | 0.86 | MERTK (0.66) | NPY5RCHEK2EGFRERBB2ROS1 | |
| Hydrochloric Acid SCHEMBL8909111 | 0.85 | MERTK (0.64) | NPY5RCHEK2EGFRERBB2ROS1 | |
| SCHEMBL8891704 | 0.82 | NPY5R (0.67) | NPY5RSLC2A1PIN1MERTK | |
| SCHEMBL8890861 | 0.82 | NPY5R (0.77) | NPY5RCHEK2EGFRERBB2ROS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |