Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MERTK | Q12866 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891572 | 0.88 | NPY5R (0.60) | NPY5RMERTKPIN1SLC2A1 | |
| SCHEMBL8891704 | 0.83 | NPY5R (0.67) | NPY5RKMT2ANPC1PKMRAB9A | |
| SCHEMBL8891002 | 0.82 | NPY5R (0.54) | NPY5RKMT2AMERTKMAPTNPSR1 | |
| SCHEMBL8900235 | 0.81 | NPY5R (0.61) | NPY5RKMT2AMERTKMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL8890646 | 0.81 | NPY5R (0.53) | NPY5RKMT2ANPC1PKMRAB9A | |
| SCHEMBL8891324 | 0.81 | NPY5R (0.61) | NPY5RKMT2ANPC1MERTKMAPT | |
| SCHEMBL8898903 | 0.81 | NPY5R (0.77) | NPY5RKMT2ANPC1RAB9AMERTK | |
| Hydrochloric Acid SCHEMBL8891027 | 0.80 | NPY5R (0.60) | NPY5RKMT2ANPC1PKMRAB9A | |
| SCHEMBL8900305 | 0.80 | EGFR (0.69) | NPY5RKMT2ANPC1PKMRAB9A | |
| SCHEMBL25760732 | 0.80 | MERTK (0.74) | NPY5RKMT2ANPC1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |