Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973840 | 0.85 | CD44 (0.33) | GAA | |
| SCHEMBL10607540 | 0.85 | GAA (0.30) | GAA | |
| Apraclonidine SCHEMBL20840496 | 0.79 | CYP3A4 (0.39) | — | |
| Apraclonidine SCHEMBL34127 | 0.79 | CYP3A4 (0.39) | — | |
| SCHEMBL6895755 | 0.79 | NOTUM (0.31) | — | |
| Apraclonidine SCHEMBL8762489 | 0.78 | BLM (0.39) | — | |
| Apraclonidine SCHEMBL22616253 | 0.78 | CYP3A4 (0.38) | — | |
| Apraclonidine SCHEMBL41138 | 0.78 | BLM (0.39) | — | |
| Hydrochloric Acid SCHEMBL10876923 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL11449342 | 0.76 | CD44 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612364-A | INTRAOCULAR HYPERTENSION | ALCON LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | claimed |
| WO-1997017331-A1 | SUBSTANTIALLY PURE APRACLONIDINE AND ITS USE IN LOWERING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1997-05-15 | — | — | WO | disclosed |
| US-5612364-A | INTRAOCULAR HYPERTENSION | ALCON LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | disclosed |