Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.53 |
| ▸ | CCR1 | P32246 | 8/20 | 0.52 |
| ▸ | CCR3 | P51677 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8893906 | 0.81 | OPRM1 (0.50) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| Hydrochloric Acid SCHEMBL7470984 | 0.80 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| Hydrochloric Acid SCHEMBL8892207 | 0.78 | OPRM1 (0.50) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| SCHEMBL8892446 | 0.78 | OPRM1 (0.50) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| SCHEMBL8901930 | 0.78 | CCR1 (0.74) | OPRM1OPRD1OPRK1CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL7465914 | 0.76 | OPRM1 (0.43) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| Hydrochloric Acid SCHEMBL8892325 | 0.74 | MAPT (0.43) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| Hydrochloric Acid SCHEMBL7458961 | 0.73 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| SCHEMBL7462099 | 0.73 | OPRM1 (0.43) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| Hydrochloric Acid SCHEMBL8891721 | 0.73 | OPRM1 (0.49) | OPRM1OPRL1OPRD1OPRK1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |