Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891603 | 0.88 | HTR2C (0.56) | HTR2AHTR2CHTR2B | |
| SCHEMBL8890510 | 0.79 | — | — | |
| SCHEMBL8332882 | 0.77 | HTR2A (0.47) | HTR2AHTR2CHTR2B | |
| SCHEMBL8329351 | 0.77 | HTR2A (0.47) | HTR2AHTR2CHTR2B | |
| SCHEMBL8332736 | 0.76 | HTR2C (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL8330683 | 0.76 | HTR2A (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL8331305 | 0.76 | HTR2A (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL23995531 | 0.74 | HTR2C (0.74) | HTR2AHTR2CHTR2B | |
| SCHEMBL22334915 | 0.74 | HTR2C (0.74) | HTR2AHTR2CHTR2B | |
| SCHEMBL20205056 | 0.74 | HTR2C (0.74) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594034-A | ADMINISTERING DIRECT ACTING 5-HYDROXYTRYPTAMINE AGONIST TO MAMMAL | ELI LILLY AND COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| US-5594025-A | Method of inhibiting gastric acid secretion with 5-substituted-3-aminochromane | ELI LILLY AND COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| US-5576352-A | Method of inhibiting gastric acid secretion with aryloxypropanolamines | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| US-5457120-A | Antisecretory and antiserotonine agents | ELI LILLY AND COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| US-5340838-A | Administering serotonin agonist to mammals | ELI LILLY AND COMPANY (US) | 1994-08-23 | — | — | US | disclosed |
| US-5258379-A | ADMINISTERING IN AN EFFECTIVE DOSAGE TO MAMMALS | ELI LILLY AND COMPANY (US) | 1993-11-02 | — | — | US | disclosed |
| US-5158956-A | Administering serotonin receptor agonist | ELI LILLY AND COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| US-5096908-A | 5-HT1A agonist | ELI LILLY AND COMPANY (US) | 1992-03-17 | — | — | US | disclosed |