Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.35 |
| ▸ | TCF7L2 | Q9NQB0 | 3/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | NPM1 | P06748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889431 | 0.76 | EGFR (0.43) | NPY5REGFRCTNNB1TCF7L2 | |
| SCHEMBL8891393 | 0.76 | SLC2A1 (0.45) | NPY5RSLC2A1 | |
| Hydrochloric Acid SCHEMBL8890271 | 0.75 | SLC2A1 (0.47) | NPY5RSLC2A1 | |
| SCHEMBL8891387 | 0.74 | NPY5R (0.69) | NPY5RSLC2A1 | |
| Hydrochloric Acid SCHEMBL8890265 | 0.73 | NPY5R (0.67) | NPY5RSLC2A1 | |
| SCHEMBL8899707 | 0.71 | NPY5R (0.58) | NPY5RSLC2A1CTNNB1TCF7L2 | |
| Hydrochloric Acid SCHEMBL8891262 | 0.70 | NPY5R (0.57) | NPY5RSLC2A1CTNNB1TCF7L2 | |
| SCHEMBL8891585 | 0.70 | NPY5R (0.77) | NPY5RSLC2A1EGFRCTNNB1TCF7L2 | |
| Hydrochloric Acid SCHEMBL8890940 | 0.69 | NPY5R (0.75) | NPY5RSLC2A1EGFRCTNNB1TCF7L2 | |
| SCHEMBL8890917 | 0.69 | NPY5R (0.65) | NPY5RSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |