Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.34 |
| ▸ | TCF7L2 | Q9NQB0 | 5/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891648 | 0.76 | NPY5R (0.41) | EGFRNPY5RCTNNB1TCF7L2 | |
| SCHEMBL8889934 | 0.72 | CTNNB1 (0.46) | CTNNB1TCF7L2P2RX3 | |
| Hydrochloric Acid SCHEMBL8889724 | 0.68 | NPY5R (0.76) | EGFRNPY5RKDM1AL3MBTL1 | |
| SCHEMBL8891133 | 0.67 | NPY5R (0.46) | NPY5RKDRCTNNB1TCF7L2MAPT | |
| SCHEMBL8893267 | 0.65 | NPY5R (0.60) | EGFRNPY5RKDM1AALDH1A1L3MBTL1 | |
| SCHEMBL8890735 | 0.64 | EGFR (0.63) | EGFRNPY5RKDM1AMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8909035 | 0.64 | NPY5R (0.59) | EGFRNPY5RKDM1AALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8888779 | 0.64 | EGFR (0.62) | EGFRNPY5RKDM1AMAPTMAPK1 | |
| SCHEMBL7254867 | 0.59 | PIN1 (0.57) | EGFRNPY5RKDRPIN1MAPT | |
| SCHEMBL8891909 | 0.58 | NPY5R (0.83) | EGFRNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |