Ethylene Glycol

Ethylene Glycol

SCHEMBL8891682

C[N+](C)(C)CC(O)COP(=O)(O)O.OCCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LPAR5 Q9H1C0 2/20 0.45
PGK1 P00558 1/20 0.44
PGK2 P07205 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LPAR1 Q92633 3/20 0.41
LPAR6 P43657 1/20 0.41
LPAR4 Q99677 1/20 0.41
LPAR2 Q9HBW0 1/20 0.41
LPAR3 Q9UBY5 1/20 0.41
ENPP2 Q13822 1/20 0.41
PGD P52209 3/20 0.41
MPI P34949 1/20 0.41
SLC22A16 Q86VW1 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6236749 0.94 LPAR5 (0.49) LPAR5PGK1PGK2SMN1; SMN2LPAR1
Glycerin SCHEMBL8890733 0.90 SMN1; SMN2 (0.50) LPAR5PGK1PGK2SMN1; SMN2LPAR1
SCHEMBL8882006 0.83 PSMD14 (0.47) LPAR5PGK1PGK2SMN1; SMN2LPAR1
SCHEMBL8884335 0.83 PSMD14 (0.47) LPAR5PGK1PGK2SMN1; SMN2LPAR1
Choline SCHEMBL29876695 0.82 SMN1; SMN2 (0.58) LPAR5PGK1PGK2SMN1; SMN2LPAR1
Choline SCHEMBL1009005 0.82 SMN1; SMN2 (0.58) LPAR5PGK1PGK2SMN1; SMN2LPAR1
SCHEMBL6236747 0.79 SMN1; SMN2 (0.44) LPAR5PGK1PGK2SMN1; SMN2LPAR1
SCHEMBL30211934 0.79 PGK1 (0.50) LPAR5PGK1PGK2SMN1; SMN2LPAR1
SCHEMBL29822621 0.79 PGK1 (0.50) LPAR5PGK1PGK2SMN1; SMN2LPAR1
Ethylene Glycol SCHEMBL8890416 0.78 LPAR5 (0.55) LPAR5LPAR1LPAR6LPAR4LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514588-B1 Novel phosphobetaine and detergent and cosmetic containing the same KAO CORP (JP) 1997-06-11 EP disclosed
US-5409705-A Phosphobetaine and detergent and cosmetic containing the same KAO CORPORATION (JP) 1995-04-25 US disclosed
EP-0514588-A2 Novel phosphobetaine and detergent and cosmetic containing the same Kao Corporation (JP) 1991-11-25 EP disclosed