Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | RPS27 | P42677 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468248 | 0.83 | MAPK8 (0.46) | NCF1TLR7KDM4EALDH1A1GAA | |
| SCHEMBL11504983 | 0.80 | AURKA (0.63) | AURKACYP2D6CYP3A4CYP1A2KDM4E | |
| SCHEMBL8891710 | 0.74 | MAPK8 (0.40) | AURKACYP2D6CYP3A4PIK3CDPIK3R1 | |
| SCHEMBL8888556 | 0.73 | MAPK8 (0.49) | TLR7KDM4EALDH1A1HPGDMAPK8 | |
| SCHEMBL11704744 | 0.72 | MAPK8 (0.54) | RPS27LMNAKDM4EALDH1A1GAA | |
| SCHEMBL8889038 | 0.72 | MAPK8 (0.48) | LMNAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL11504969 | 0.72 | GBA1 (0.43) | NCF1NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL8889019 | 0.71 | MAPK8 (0.47) | AURKALMNAKDM4EALDH1A1GAA | |
| SCHEMBL11675936 | 0.71 | DRD4 (0.55) | ALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL11701910 | 0.70 | ADORA1 (0.52) | AURKALMNAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602238-A | FOR DYEING POLYESTER FIBERS COLORFAST RED SHADES | CIBA-GEIGY CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0699718-A2 | Azothiophene dyes with a 2,4,6-triamino-3-cyanopyridine coupling component | CIBA-GEIGY AG (CH) | 1996-03-06 | — | — | EP | disclosed |
| US-5196521-A | Colorfastness; red; polyesters | CIBA-GEIGY CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |