Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 7/20 | 0.40 |
| ▸ | RPS27 | P42677 | 4/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611877 | 0.91 | CYP2D6 (0.43) | MAPK8RPS27AURKACYP3A4CYP2D6 | |
| SCHEMBL9468250 | 0.85 | MAPK8 (0.38) | MAPK8RPS27MAPK9MAPK10ALDH1A1 | |
| SCHEMBL8891696 | 0.81 | MAPK8 (0.38) | MAPK8RPS27MAPK9MAPK10PRKD3 | |
| SCHEMBL11504988 | 0.81 | AURKA (0.50) | AURKACYP3A4CYP2D6ALDH1A1KDM4E | |
| SCHEMBL11454175 | 0.76 | MAPK8 (0.43) | MAPK8RPS27MAPK9MAPK10PRKD3 | |
| SCHEMBL11506766 | 0.76 | AURKA (0.34) | AURKACYP3A4CYP2D6LMNAALDH1A1 | |
| SCHEMBL8891703 | 0.74 | AURKA (0.47) | MAPK8RPS27AURKACYP3A4CYP2D6 | |
| SCHEMBL9468243 | 0.74 | MAPK8 (0.41) | MAPK8RPS27MAPK9MAPK10ALDH1A1 | |
| SCHEMBL11504974 | 0.73 | MEN1 (0.40) | NPC1LMNARAB9AALDH1A1HTR7 | |
| SCHEMBL11326488 | 0.72 | ALDH1A1 (0.37) | MAPK8RPS27AURKACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602238-A | FOR DYEING POLYESTER FIBERS COLORFAST RED SHADES | CIBA-GEIGY CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0699718-A2 | Azothiophene dyes with a 2,4,6-triamino-3-cyanopyridine coupling component | CIBA-GEIGY AG (CH) | 1996-03-06 | — | — | EP | disclosed |
| US-5196521-A | Colorfastness; red; polyesters | CIBA-GEIGY CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |