Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.67 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.59 |
| ▸ | MERTK | Q12866 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PGK1 | P00558 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892796 | 0.93 | NPY5R (0.76) | NPY5RTAAR1HTTSMN1; SMN2PIN1 | |
| SCHEMBL8890204 | 0.89 | HTT (0.68) | NPY5RTAAR1HTTSMN1; SMN2MERTK | |
| SCHEMBL8890113 | 0.85 | NPY5R (0.58) | NPY5RTAAR1HTTPOLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8906400 | 0.84 | NPY5R (0.57) | NPY5RTAAR1HTTPOLBSMN1; SMN2 | |
| SCHEMBL8900305 | 0.84 | EGFR (0.69) | NPY5RPIN1MERTKKMT2ASLC2A1 | |
| SCHEMBL8891978 | 0.83 | NPY5R (0.65) | NPY5RHTTPOLBSMN1; SMN2PIN1 | |
| Hydrochloric Acid SCHEMBL8899588 | 0.82 | CHEK2 (0.67) | NPY5RTAAR1HTTPOLBSMN1; SMN2 | |
| SCHEMBL8891572 | 0.82 | NPY5R (0.60) | NPY5RPIN1MERTKSLC2A1 | |
| SCHEMBL8898903 | 0.82 | NPY5R (0.77) | NPY5RHTTSMN1; SMN2PIN1MERTK | |
| Hydrochloric Acid SCHEMBL8916013 | 0.81 | NPY5R (0.76) | NPY5RTAAR1HTTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |