Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TPH1 | P17752 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891766 | 1.00 | LDHA (0.56) | LDHAPPARGKMT2ASLC6A4SLC1A3 | |
| SCHEMBL7439269 | 0.96 | SLC1A3 (0.54) | LDHAPPARGKMT2ASLC1A3SLC1A2 | |
| SCHEMBL8893679 | 0.96 | SLC1A3 (0.54) | LDHAPPARGKMT2ASLC1A3SLC1A2 | |
| SCHEMBL8893674 | 0.96 | SLC1A3 (0.54) | LDHAPPARGKMT2ASLC1A3SLC1A2 | |
| SCHEMBL7439274 | 0.96 | SLC1A3 (0.54) | LDHAPPARGKMT2ASLC1A3SLC1A2 | |
| SCHEMBL8892841 | 0.95 | LDHA (0.51) | LDHAPPARGKMT2ASLC6A4SLC1A3 | |
| SCHEMBL8892836 | 0.95 | LDHA (0.51) | LDHAPPARGKMT2ASLC6A4SLC1A3 | |
| SCHEMBL8895252 | 0.91 | TAAR1 (0.49) | LDHAPPARGSLC6A4SLC1A3SLC1A2 | |
| SCHEMBL8895260 | 0.91 | TAAR1 (0.49) | LDHAPPARGSLC6A4SLC1A3SLC1A2 | |
| SCHEMBL8893456 | 0.89 | LTA4H (0.61) | LDHAPPARGSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |