Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13247707 | 0.77 | NPSR1 (0.54) | NPSR1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL19738005 | 0.74 | NPSR1 (0.50) | NPSR1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7944992 | 0.74 | NPSR1 (0.50) | NPSR1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL17831838 | 0.73 | NPSR1 (0.48) | NPSR1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL13242308 | 0.70 | FBP1 (0.62) | NPSR1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL8893238 | 0.70 | NPSR1 (0.45) | NPSR1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL30703864 | 0.70 | KDM4E (0.44) | NPSR1L3MBTL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30703771 | 0.70 | KDM4E (0.41) | NPSR1L3MBTL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28635642 | 0.70 | KDM4E (0.41) | NPSR1L3MBTL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2720833 | 0.69 | NPSR1 (0.44) | NPSR1L3MBTL1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |