Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.49 |
| ▸ | F10 | P00742 | 6/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893076 | 0.90 | ITGB3 (0.45) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL7461194 | 0.86 | ITGB3 (0.55) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL7461204 | 0.80 | ITGB3 (0.51) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL8894267 | 0.79 | PRSS1 (0.51) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL7463121 | 0.77 | ITGB3 (0.43) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL7461876 | 0.77 | F10 (0.45) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL8892670 | 0.76 | NPC1 (0.40) | ITGB3POLB | |
| SCHEMBL7462105 | 0.75 | F10 (0.51) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL8892077 | 0.75 | ITGB3 (0.43) | PRSS1PRSS2PRSS3ITGB3ITGA2B | |
| SCHEMBL7462601 | 0.74 | PRSS1 (0.41) | PRSS1PRSS2PRSS3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |