Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.45 |
| ▸ | F10 | P00742 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891945 | 0.90 | PRSS1 (0.49) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7463121 | 0.87 | ITGB3 (0.43) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7462105 | 0.87 | F10 (0.51) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8892670 | 0.86 | NPC1 (0.40) | ITGB3MAPTNAMPT | |
| SCHEMBL7462114 | 0.81 | PRSS1 (0.47) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7461796 | 0.78 | F10 (0.41) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8894267 | 0.76 | PRSS1 (0.51) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7461194 | 0.76 | ITGB3 (0.55) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8892667 | 0.76 | HPGD (0.37) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7461804 | 0.72 | F10 (0.39) | ITGB3PRSS1PRSS2ITGA2BPRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |