SCHEMBL8891958

SCHEMBL8891958

Brc1cccnc1-c1cnccn1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIEZO1 Q92508 3/20 0.40
CYP2A6 P11509 3/20 0.40
TERT O14746 2/20 0.40
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
METAP2 P50579 1/20 0.37
PIM1 P11309 1/20 0.36
AXL P30530 1/20 0.35
CDC25B P30305 1/20 0.35
CYP1A2 P05177 2/20 0.35
KDR P35968 1/20 0.34
NISCH Q9Y2I1 1/20 0.34
NPC1 O15118 2/20 0.34
PKM P14618 2/20 0.34
RAB9A P51151 2/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
POLB P06746 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30189385 0.78 KDM4E (0.54) CYP2A6PIM1CYP1A2NPC1PKM
SCHEMBL4612674 0.78 KDM4E (0.54) CYP2A6PIM1CYP1A2NPC1PKM
SCHEMBL29604515 0.77 PIEZO1 (0.40) PIEZO1CYP2A6METAP2NPC1PKM
SCHEMBL29666462 0.76 CDC25B (0.46) AXLCDC25BCYP1A2NPC1TP53
SCHEMBL28540095 0.76 NISCH (0.45) ADORA2AADORA1METAP2PIM1CYP1A2
SCHEMBL7772699 0.76 CDC25B (0.46) AXLCDC25BCYP1A2NPC1TP53
SCHEMBL8892515 0.76 PIEZO1 (0.37) PIEZO1TERTADORA2AADORA1METAP2
Pyridine SCHEMBL28835501 0.76 CYP2A6 (0.47) CYP2A6PIM1CYP1A2NPC1PKM
SCHEMBL29933878 0.74 CYP2A6 (0.61) CYP2A6ADORA2ACYP1A2NPC1RAB9A
SCHEMBL4072793 0.74 IDO1 (0.47) PIEZO1CYP2A6TERTMETAP2PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5626791-A FERROELECTRIC LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-06 US disclosed