Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007440 | 0.79 | MAPT (0.50) | ALDH1A1MAPTACHEKDM4EGAA | |
| SCHEMBL2448841 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL4902020 | 0.75 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDGLAACHE | |
| Acridine SCHEMBL10533085 | 0.71 | ALDH1A1 (0.71) | ALDH1A1MAPTHPGDGLAACHE | |
| Acridine SCHEMBL28002752 | 0.71 | ALDH1A1 (0.71) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL1228778 | 0.71 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL28573272 | 0.71 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL1188539 | 0.71 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL38655484 | 0.71 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL9559949 | 0.71 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDGLAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027179-A2 | ANTIRETROVIRAL BASES | NOVARTIS AG (CH) | 1997-07-31 | — | — | WO | disclosed |